During this webinar Dr. Michelle McDonald will discuss using a novel intravital imaging technique to visualise tumour cell fate, bone cell dynamics and tumour-bone cell interactions we have advanced our fundamental understanding of tumour cell dormancy and osteoclast biology, and uncovered mechanisms behind clinical responses to anti-resorptive therapies. Through targeting this novel cell biology, we are defining strategies to prevent bone loss in patients who are withdrawn from anti-RANKL therapy. We are also investigating new approaches to prevent bone metastatic tumours indirectly through targeting the bone microenvironment.
