Webinars are hosted by the ISBM Early Career Investigator Committee and are open to members and non-members of ISBM at all career stages. Priority is given to Early Career Investigators to introduce themselves and meet the speaker at the end of the webinar. Our goal is to support students and fellows that are interested in joining an active community of researchers focused on the quantitative imaging and analysis of skeletal tissues (histomorphometry, immunostaining, lineage tracing, live imaging, CT, tissue clearing, morphometrics, spatial transcriptomics, etc).
During this webinar Dr. Thomas Andersen will discuss how thousands of bone remodeling units (BRUs) constantly renew our bones throughout our lives. These units are also known as basic multicellular units (BMUs) and involves a highly coordinated bone resorption and formation. This webinar will cover the recently revised phases of the BMUs and the key […]
During this webinar Dr. Graeme Campbell will discuss how computed tomography (CT) is considered the “workhorse” of diagnostic imaging in almost all clinical subdisciplines. It is indispensable in terms of its availability, standardization, examination speed and options for integration into complex clinical workflows. In the musculoskeletal (MSK) domain, CT provides high-resolution images of bony structures, […]
During this webinar Dr. Sarah Dallas will discuss using live cell imaging in combination with transgenic mice expressing GFP-tagged collagen and fluorescent reporters to visualize bone cell lineages, our work has advanced fundamental understanding of bone extracellular matrix assembly and resorption dynamics. Live cell imaging has revealed the dynamic mechanisms of osteocyte embedding in collagen […]
During this webinar Dr. Michelle McDonald will discuss using a novel intravital imaging technique to visualise tumour cell fate, bone cell dynamics and tumour-bone cell interactions we have advanced our fundamental understanding of tumour cell dormancy and osteoclast biology, and uncovered mechanisms behind clinical responses to anti-resorptive therapies. Through targeting this novel cell biology, we […]
During this webinar, Dr. Ralph Müller will delve into the intricate field of multiscale bone biomechanics and imaging. From milliseconds to years and nanometers to centimeters, bone biomechanics require integrating information across various scales. Explore Dr. Müller’s research, which combines mechanics and microstructural imaging, employing computer simulations and experimental validation. Discover image-guided techniques that provide […]
During this webinar, Dr. Leigh Gabel will discuss the importance of movement (physical activity and exercise) during childhood and adolescence for developing a healthy skeleton and how different imaging modalities (e.g., DXA, pQCT, HR-pQCT) help us understand the intricacies of bone accrual. Dr. Gabel will also discuss how prolonged unloading (i.e., long-duration spaceflight) impacts bone […]